Drug Repositioning for Ovarian Cancer Treatment: An Update
- Авторлар: Cavalluzzi M.1, Viale M.2, Rotondo N.3, Ferraro V.1, Lentini G.1
-
Мекемелер:
- Department of Pharmacy Drug Sciences, University of Bari Aldo Moro
- UOC Biotherapy, IRCCS San Martino Hospital
- Pharmacy - Drug Sciences, University of Bari Aldo Moro
- Шығарылым: Том 24, № 8 (2024)
- Беттер: 637-647
- Бөлім: Oncology
- URL: https://snv63.ru/1871-5206/article/view/644289
- DOI: https://doi.org/10.2174/0118715206282904240122063914
- ID: 644289
Дәйексөз келтіру
Толық мәтін
Аннотация
Ovarian cancer (OC) is one of the most prevalent malignancies in female reproductive organs, and its 5-year survival is below 45%. Despite the advances in surgical and chemotherapeutic options, OC treatment is still a challenge, and new anticancer agents are urgently needed. Drug repositioning has gained significant attention in drug discovery, representing a smart way to identify new clinical applications for drugs whose human safety and pharmacokinetics have already been established, with great time and cost savings in pharmaceutical development endeavors. This review offers an update on the most promising drugs repurposable for OC treatment and/or prevention.
Негізгі сөздер
Авторлар туралы
Maria Cavalluzzi
Department of Pharmacy Drug Sciences, University of Bari Aldo Moro
Хат алмасуға жауапты Автор.
Email: info@benthamscience.net
Maurizio Viale
UOC Biotherapy, IRCCS San Martino Hospital
Email: info@benthamscience.net
Natalie Rotondo
Pharmacy - Drug Sciences, University of Bari Aldo Moro
Email: info@benthamscience.net
Valeria Ferraro
Department of Pharmacy Drug Sciences, University of Bari Aldo Moro
Email: info@benthamscience.net
Giovanni Lentini
Department of Pharmacy Drug Sciences, University of Bari Aldo Moro
Email: info@benthamscience.net
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