电邮这篇文章 ASSESSMENT OF EATING BEHAVIOR AND DYNAMIC OF WEIGHT GAIN OF EXPERIMENTAL ANIMALS WITH A SINGLE RECEIPT OF THE MIXED OXIDE OF DEPLETED URANIUM WITH WATER
- 作者: Gerasimov D.V.1
-
隶属关系:
- I.M. Sechenov First Moscow State Medical University, RF Ministry of Health
- 期: 编号 2 (2018)
- 页面: 53-56
- 栏目: Articles
- ##submission.datePublished##: 28.04.2018
- URL: https://snv63.ru/0869-7922/article/view/641086
- DOI: https://doi.org/10.36946/0869-7922-2018-2-53-56
- ID: 641086
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The experiment on the study of food behavior and the dynamics of weight gain in experimental animals (rats) after single oral intake of the mixed oxide of depleted uranium (U3O8 + UO2) with water is given. It is shown that when depleted uranium enters the body, rodent eating behavior increases possibly due to direct neurotoxicity of uranium compounds, as well as impaired metabolism of neurotransmitters in a brain. At the same time, the toxic effect of uranium compounds on the organs of the gastrointestinal tract is probably the cause of malabsorption syndrome, which causes a decrease in weight gain in animals.
作者简介
D. Gerasimov
I.M. Sechenov First Moscow State Medical University, RF Ministry of Health
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Email: noemail@neicon.ru
俄罗斯联邦
参考
- Eldaghmah M. Radiation doses arising from depleted uranium shells. Environmental Science, ESAIJ. 2015; 10(7): 249–253.
- Заключение специалистов межведомственной группы экспертов по рассмотрению последствий применения силами НАТО в Югославии боеприпасов с обеднённым ураном. / Совместный Приказ Минатом РФ, МО РФ и Минздрава РФ (№ 96/81/53 от 22.02.2001.). М.: 2001.
- Oakford S. The United States Used Depleted Uranium in Syria. Foreign Policy, 2017. Available at: https://foreignpolicy. com/2017/02/14/the-united-states-useddepleteduranium-in-syria
- Pititot F., Lestaevel P., Tourionias E. еt al. Inhalation of uranium nanoparticles: Respiratory tract deposition and translocation to secondary target organs in rats. Toxicol. Lett. 2013; 1: 217–225.
- Shaki F., Hosseini M., Ghazi-Khansari M. еt al. Depleted uranium induces disruption of energy homeostasis and oxidative stress in isolated rat brain mitochondria. Metallomics. 2013; (5): 736–744.
- Tasat D.R., Orona N.S., Bozal C. еt al. Intercellular Metabolism of Uranium and the Effects of Bisphosphonates on Its Toxicity. In Cell Metabolism-Cell Homeostasis and Stress Response. Tech Publishers: Rijeka, Yugoslavia. 2012.
- Hon Z., Österreicher J., Navrátil L. Depleted Uranium and Its Effects on Humans. Sustainability. 2015; (7): 4063–4077.
- Герасимов Д.В. Анализ функциональных изменений центральной нервной системы грызунов при однократном поступлении смешанного оксида обедненного урана с водой. Токсикологический вестник, Москва. 2017; (1): 42–46.
- Gueguen Y., Rouas C., Monin A. еt al. Molecular, cellular and tissue impact of depleted uranium xenobiotic-metabolizing enzymes. Arch. Toxicol. 2013.
- Калистратова В.С., ред. Радиобиология инкорпорированных радионуклидов. М.: ГНЦ РФ ФГБУ «ФМБЦ им. А.И. Бурназяна ФМБА России»; 2012.
- Katz S.A. The Chemistry and Toxicology of Depleted Uranium. Toxics. 2014; (2): 50–78.
- Буреш Я., Бурешова О., Хьюстон Д. Методики и основные эксперименты по изучению мозга и поведения (перевод с англ.). М.: Высшая школа; 1991.
- Barillet S., Adam C., Palluel O., Devaux A. Bioaccumulation, oxidative stress and neurotoxicity in Danio Rerio exposed to different isotopic compositions of uranium. Environmental Toxicology and Chemistry. 2007; 26(3): 497–505.
- Lestaevel P., Airault F., Racine R. еt al. Influence of environmental enrichment and depleted uranium on behaviour, cholesterol and acetylcholine in apolioprotein E-defivient mice. J. Mol. Neurosci. 2013;(1): 31–38.
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